Phytoconstituents and Biological Activities of Zanthoxylum armatum Fruit Extract

نویسندگان

چکیده

The essential oil and methanol extract of the fruit Zanthoxylum armatum DC were extracted by hydro-distillation in Clevenger apparatus cold percolation technique respectively their chemical biological studies performed. compositions analyzed GC-MS analysis. most abundant ingredient was Linalool (75.31%) followed E-methyl cinnamate (11.73%) limonene (9.45%). nature functional groups present performing FTIR showed presence alkaloids, flavonoids, glycosides, polyphenols, terpenoids, volatile oils, tannins, saponins. Biological activities evaluated brine shrimp bioassay, antibacterial activity test, antifungal test. Essential (LC50 = 76.70 µg/mL) 62.25 found highly cytotoxic against brine-shrimp nauplii. potent gram-positive bacteria Bacillus subtilis, Micrococcus leutus, Staphylococcus aureus with zone inhibitions 11 mm, 16 17 mm moderate gram-negative Klebsiella pneumonia, Enterobacter cloacae, Pseudomonas aeruginosa 9 5 6 respectively. to be effective only. Both bacterial strains.

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ژورنال

عنوان ژورنال: Journal of Nepal Chemical Society

سال: 2021

ISSN: ['2091-0304']

DOI: https://doi.org/10.3126/jncs.v42i1.35363